Innovation Saving Lives

We are a biotechnology company with a proprietary biomarker discovery platform, EpiSwitch™, based on the latest advances in gene expression,non-coding RNA and epigenetics.

Episwitch™ biomarkers based on chromosomal conformation signatures are a critical cog in personalised medicine.

Technology to select the right drug at the right dose at the right time for the right patient.

Recent Publications on Chromosome Conformation Signatures


Capturing genomic relationships that matter.

Osborne CS et. al.
Chromosome Research
https://www.ncbi.nlm.nih.gov/pubmed/28078515

A pathway-centric view of spatial proximity in the 3D nucleome across cell lines.

Karathia et. al.
Scientific Reports
http://www.nature.com/articles/srep39279

Disruption of the 3D cancer genome blueprint.

Aching-Kawecka et. al.
Epigenomics
http://www.futuremedicine.com/doi/abs/10.2217/epi-2016-0111

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease.

Meddens et. al.
Genome Biology
https://www.ncbi.nlm.nih.gov/pubmed/27903283

Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C.

Martin et. al.
PLOS ONE
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166923