Bioinformatics Scientist
Full time, permanent
Location: Oxford
Job advert closes 24 Mar 2020
Competitive salary
The successful applicant will be Responsible for:
• Interrogate microarray data, PCR, qPCR data and NGS dataset of ultra deep sequencing and develop analytical techniques to investigate chromosome conformation capture data in collaboration with internal and external customers.
• Provide more basic statistical support for follow-up work with biology teams to analyse and implement systems biology analysis methods across a range of data types to create biological in-silico networks for biological insights.
• Develop novel strategies to integrate and analyse multi-omics and other types of data for discovery of biomarkers and new targets.
• Work with others in the team to implement data analysis pipelines with user-friendly interface suitable for biologists to process, analyse, and interpret data.
• Analyse RNAseq, ATACseq and ChIPseq data for chromatin conformational studies
Summary of Skills, Experience and Qualifications
Essential
• BSc/MSc in Bioinformatics; or strong data analysis skills gained in other fields, e.g. computational biology, mathematics or physics
• Research experience of programming/data analysis/development
• Skills in at least one of the programming languages: Python, Perl, Java, C/C++
• Skills in R, SQL, HTML, JavaScript and knowledge of Unix/Linux environment and the ability to learn new programming skills as required
• Knowledge of statistical analysis of relevance to biological research & large datasets, cloud-scale data processing, high-performance computing, web technologies
• Knowledge of bioinformatics and statistics techniques commonly applied for clinical biology, machine learning/AI, linear and non-linear modelling and data-mining algorithms
• Ability to work in a multidisciplinary team
• Ability to work independently with minimal supervision, but also operating as part of a team, providing direction and guidance as required
• Demonstration of initiative and ability to conceive, design and execute appropriate experimental analyses and draw conclusions from the outcomes
• Excellent presentation skills
• Flexibility and willingness to work out of regular hours if required
Desirable
• Familiarity with molecular biology/structural biology/chromatin conformation concepts and principles
• Evidence of interest in clinical/translational research
• Sound knowledge of standard bioinformatics tools, algorithms and techniques
• Major contribution to at least one paper in a peer-reviewed journal
• Expertise in one or more of the core competency areas: network biology, multivariate and/or high dimensional data analysis (-omics), knowledge engineering, ontologies, data management, text mining, NLP, machine learning, statistical modelling, multivariate data analysis, classification/regression
• Extensive relevant postdoctoral experience
• Experience of mentoring, coaching and development of colleagues
• Experience and confidence in presenting research findings at national and international meetings
We offer a competitive salary, auto enrolment into The Peoples Pension Scheme (5% paid by company 3% paid by employee), 20 days holiday plus statutory holiday and a choice to sign up for medical insurance.
No agencies please.
Please send a copy of your CV and a cover letter to
humanresources@oxfordbiodynamics.com