Innovation Saving Lives

We are a biotechnology company with a proprietary biomarker discovery platform, EpiSwitch™, based on the latest advances in gene expression,
non-coding RNA and epigenetics.

EpiSwitch™ biomarkers based on chromosomal conformation signatures are a critical cog in personalised medicine.

Technology to select the right drug at the right dose at the right time for the right patient.

EpiSwitch™ captures the heterogeneity of the environment on the genome.

 

To learn more, read our White Paper

Recent Publications on Chromosome Conformation Signatures


Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming.

Stadhouders R, et. al.
Nat Genet.
https://www.ncbi.nlm.nih.gov/pubmed/?term=Transcription+factors+orchestrate+dynamic+interplay+between+genome+topology+and+gene+regulation+during+cell+reprogramming

Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries.

Gong Y, et. al.
Nat Commun.
https://www.ncbi.nlm.nih.gov/pubmed/29416042

OneD: increasing reproducibility of Hi-C samples with abnormal karyotypes.

Vidal E, et. al.
Nucleic Acids Res.
https://www.ncbi.nlm.nih.gov/pubmed/29394371

Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions.

Sun et. al.
Nanotoxicology
https://www.ncbi.nlm.nih.gov/pubmed/29338479

Detecting hierarchical genome folding with network modularity.

Norton et. al.
Nat Methods
https://www.ncbi.nlm.nih.gov/pubmed/29334377