Innovation Saving Lives

We are a biotechnology company with a proprietary biomarker discovery platform, EpiSwitch™, based on the latest advances in gene expression,non-coding RNA and epigenetics.

EpiSwitch™ biomarkers based on chromosomal conformation signatures are a critical cog in personalised medicine.

Technology to select the right drug at the right dose at the right time for the right patient.

EpiSwitch™ captures the heterogeneity of the environment on the genome.

Recent Publications on Chromosome Conformation Signatures


Generative modeling of multi-mapping reads with mHi-C advances analysis of Hi-C studies.

Zheng, Y., et. al.,
Elife
https://doi.org/10.7554/eLife.38070

InTAD: chromosome conformation guided analysis of enhancer target genes.

Okonechnikov, K., et. al.,
BMC Bioinformatics
https://doi.org/10.1186/s12859-019-2655-2

MACPET: model-based analysis for ChIA-PET.

Vardaxis, I, et. al.,
Biostatistics
https://doi.org/10.1093/biostatistics/kxy084

Non-coding RNAs and chromatin domains.

Yamamoto, T., et. al.,
Curr. Opin. Cell Biol.
https://doi.org/10.1016/j.ceb.2018.12.005

Spatial Principles of Chromatin Architecture Associated With Organ-Specific Gene Regulation

Chapski, DK., et. al.,
Front. Cardiovasc. Med.
https://doi.org/10.3389/fcvm.2018.00186