OBD contributes a chapter to the newly published "Clinical and Statistical Consideration in Personalized Medicine”.

The chapter outlines the current developments used to investigate the function epigenetics plays in understanding personalized medicine. CRC Press. Editors: Claudio Carini (Pfizer); Sandeep Menon (Pfizer), Mark Chang (AMAG Pharmaceuticals). Book available at: CRC Press website. A review of the book was published in  Journal of Biopharmaceutical Statistics.


Formation of distinct chromatin conformation signatures epigenetically regulate macrophage activation.

A collaboration between Oxford BioDynamics and Professor Siamon Gordon (Oxford University), has utilised EpiSwitch™ technology for successful identification of regulatory chromosome conformation signatures as epigenetic biomarkers for innate, alternative and classical activation states in macrophages stimulated with LPS, IL-4 and IFN-γ. Available at: International Immunopharmacology 2014 Jan;18(1):7-11


Dr. Alexandre Akoulitchev presents a poster at the 12th annual Northeast ALS Consortium (NEALS).

Each year NEALS holds an annual conference to review current ALS research, discuss potential new therapies, and prepare member-sites for clinical trials in ALS. Dr. Alexandre Akoulitchev presented this poster on the "Development of novel ALS treatment on the basis of mechanisms of cellular chronological life span control" in October 2013.